This paper argues that climate change adaptation in the health sector requires decisions across sectors, levels of government, and organisations. The study uses social network research to identify key organisational players engaged in developing health-related adaptation activities in Cambodia. It finds that strong partnerships are reported as developing across sectors and different types of organisations in relation to the health risks from climate change. Government ministries are influential organisations, whereas donors, development banks and non-government organisations do not appear to be as influential in the development of adaptation policy in the health sector. Finally, the study highlights the importance of informal partnerships (or ‘shadow networks’) in the context of climate change adaptation policy and activities. The paper develops a health governance ‘map’ in relation to health and climate change adaptation to identify organisations that are perceived as key agents in the decision-making process.