This report presents the case study of a Transfer of Environmentally Sound Technology methodology in different industries along a river basin in Honduras during the period 2008-2012. The project has managed, in three years, to bring about considerable changes to the three participating companies, all reporting a reduced contaminant concentration of their effluents as well as reduced costs, proving that green industrial processes are beneficial to both the environment and the financiers. The participating companies are now replicating the successes of the methodology in the other branches of their industrial group.