This manual should provide professional guidance on how to service and maintain refrigeration systems operating with new technology, e.g. ozone- and climate-friendly alternative refrigerants to CFCs and HCFCs. It addresses essential know-how on containment of HFC refrigerants which have a high global warming potential (GWP) and provides information on the safe use of environmental-friendly natural refrigerants, such as CO2, ammonia or hydrocarbons.