Although climate change affects men and women differently, there are few studies on specific adaptation practices disaggregated by gender. This study aims to fill this gap by analysing adaptation practices to the effects of climate change in the Bahi and Kondoa districts of the Dodoma region, Tanzania. It examines perceptions of climate change and identifies elements influencing adaptation practices. A sample of 360 respondents, 12 focus groups and 78 key informants were consulted; the analysis involved descriptive statistics for quantitative data and content analysis for qualitative data. The results reveal that women are more committed to adaptation practices that enable them to adapt to or reduce food, water and firewood shortages, while men are more dedicated to practices that enable them to adapt to or reduce effects of climate change on crops, livestock and the environment. The findings hope to assist in formulating appropriate adaptation practices for the agriculture sector.