This report is a contribution to the UNIDO ongoing programme in the chiller sector and should serve to guide countries in preparing strategies for the replacement of chlorofluorocarbon (CFC)-based chillers. It presents the issue of chiller replacements in connection with ozone depletion and energy efficiency/climate change, while outlining mechanisms that may be employed to support and accelerate chiller replacements. The report targets stakeholders that are involved in chiller replacement projects, such as engineering facilities and energy contracting providers, investors, financial institutions, government entities and private sector stakeholders.