Technology Description: Numerous diseases are spread by mosquitoes. One example Dengue virus is a mosquito born virus that infects ~250 million humans per year. The spread of mosquito-borne diseases can be restricted by decreasing mosquito populations in areas of high pathogen transmission. The new technology developed is a compound developed using thiopyran methodology that has a unique hit in mosquito assays. The novel compound FL-II-185 is a new class of mosquito selective inhibitor of blood feeding female mosquitoes. The compound inhibits nutrient processing in mosquitoes and is lethal. Additionally the screening method used to identify the compound FL-II-185 could be used to identify additional mosquito-selective inhibitors of blood meal metabolism. Patent Information: Patent Pending
1) Targets blood feeding female mosquitoes using biochemistry. 2) Does not work by neurotoxicity. 3) Safe for use in agricultural areas. 4) Not lethal in other insects such as bees. 5) Potential use in other arthropods which feed on human blood.