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This guideline aims to provide a general idea of the different steps when planning a conversion from an existing production system of domestic refrigerators to one that uses hydrocarbons, such as isobutane (R600a) or propane (R290), and the important aspects that small- to medium-size manufacturers need to consider. The holistic approach of this guideline makes it a good starting point of information, not only for directors and managers of enterprises responsible for technical aspects, product development, production line and training, but also for consultants, training institutions, teachers, lecturers and technicians.